par Boly, Raïnatou 
;Lamkami, Touria ;Lompo, Marius ;Dubois, Jacques ;Guissou, Innocent
Référence International Journal of Toxicological and Pharmacological Research, 8, 1, page (29-34)
Publication Publié, 2016-02
;Lamkami, Touria ;Lompo, Marius ;Dubois, Jacques ;Guissou, Innocent Référence International Journal of Toxicological and Pharmacological Research, 8, 1, page (29-34)
Publication Publié, 2016-02
Article révisé par les pairs
| Résumé : | Agelanthus dodoneifolius (Loranthaceae) commonly named African mistletoe is traditionally used in Burkina Faso as a decoction for the treatment of asthma, stomach-ache and cardiovascular diseases. The current study was designed to assess the DPPH free radical scavenging effect and the flavonoid and phenolic contents of the decoction and maceration extracts from Agelanthus dodoneifolius leaves. Moreover, the phytochemical analysis was also carried out. The decoction and maceration were prepared in water. Phytochemical analysis was realized according to the standard protocols. The scavenging activity was determined using the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The flavonoid and phenolic contents were assessed using the Neu and Folin-Ciocalteu reagents, respectively. The phytochemical investigation showed the presence of flavonoid, tannins, steroids, triterpenes, carotenoids, anthocyanins and sugars in Agelanthus dodoneifolius dried and powdered leaves. Both decoction and maceration exhibited a significant dose-dependent radical scavenging activity with EC50 values of 8.20 ± 0.25 and 13.20 ± 0.37 μg/mL, respectively. This significant radical scavenging effect may be attributed to their richness in flavonoid and phenolic compounds. This study enhances the ability of Agelanthus dodoneifolius leaves as excellent natural source for antiradical scavenging. Therefore, the results may be taken account for the development of an herbal medicine to treat diseases related to an oxidative damage. |
