Talactoferrin in Severe Sepsis: Results From the Phase II/III Oral tAlactoferrin in Severe sepsIS Trial

Vincent, Jean Louis; Marshall, John C; Dellinger, Richard Phillip; Simonson, Steven S.G.; Guntupalli, Kalpalatha; Levy, Mitchell; Singer, Mervyn; Malik, Rajesh

doi:doi/10.1097/CCM.0000000000001090

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Talactoferrin in Severe Sepsis: Results From the Phase II/III Oral tAlactoferrin in Severe sepsIS Trial

par Vincent, Jean Louis

;Marshall, John C ;Dellinger, Richard Phillip ;Simonson, Steven S.G.;Guntupalli, Kalpalatha ;Levy, Mitchell ;Singer, Mervyn ;Malik, Rajesh
Référence Critical care medicine, 43, 9, page (1832-1838)
Publication Publié, 2015-09

Article révisé par les pairs

Résumé :

OBJECTIVE: Talactoferrin alfa is a recombinant form of the human glycoprotein, lactoferrin, which has been shown to have a wide range of effects on the immune system. This phase II/III clinical trial compared talactoferrin with placebo, in addition to standard of care, in patients with severe sepsis.

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