Article révisé par les pairs
Résumé : After 8 yr experience of systematic screening for asymptomatic uterine cancer in 115,604 cases, the authors report the following conclusions. The cytological method is useful because it makes it possible to diagnose 2.2% of cancerous lesions in an asymptomatic population. The percentage of false positives or false negatives is negligible in a laboratory with well trained staff. The disparity between the number of noninvasive and invasive cervical epitheliomas indicates that a certain percentage of noninvasive forms do not evolve into the invasive form. The number of cancers discovered has remained constant over the years; this could be explained in several ways: insufficient effort has been made to organize mass screening; the populations effected by the screening campaigns do not represent the high risk groups (older women and the poorer social classes); slowly evolving cervical lesions are more likely to be detected than those that develop rapidly and have a less favorable prognosis. The efficiency of screening campaigns could be improved by providing better information to the public and to the medical profession on the advantages of the technique. In the absence of a precise biological definition of the intraepithelial cancerous lesion, systematic screening for the so called dysplasic or intraepithelial lesions should be continued and adequate conservative treatment must be provided.