Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: a meta-analysis.

Becquet, Renaud; Marston, Milly; Dabis, François; Moulton, Lawrence H; Gray, Glenda; Coovadia, Hoosen M; Essex, Max; Ekouevi, Didier K; Jackson, Debra; Coutsoudis, Anna; Kilewo, Charles; Leroy, Valériane; Wiktor, Stefan Z; Nduati, Ruth; Msellati, Philippe; Zaba, Basia; Ghys, Peter D; Newell, Marie-Louise; Castetbon, Katia

doi:doi/10.1371/journal.pone.0028510

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Article révisé par les pairs

Résumé :

Assumptions about survival of HIV-infected children in Africa without antiretroviral therapy need to be updated to inform ongoing UNAIDS modelling of paediatric HIV epidemics among children. Improved estimates of infant survival by timing of HIV-infection (perinatally or postnatally) are thus needed.

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