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PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

par Moore, Fabrice ;Colli, Maikel Luis ;Cnop, Miriam ;Igoillo Esteve, Mariana ;Cardozo, Alessandra K ;Andrade Da Cunha, Daniel ;Bugliani, Marco;Marchetti, Piero;Eizirik, Decio
Référence Diabetes (New York, N.Y.), 58, 6, page (1283-1291)
Publication Publié, 2009-06

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Titre:	PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.
Auteur:	Moore, Fabrice; Colli, Maikel Luis; Cnop, Miriam; Igoillo Esteve, Mariana; Cardozo, Alessandra K; Andrade Da Cunha, Daniel; Bugliani, Marco; Marchetti, Piero; Eizirik, Decio
Informations sur la publication:	Diabetes (New York, N.Y.), 58, 6, page (1283-1291)
Statut de publication:	Publié, 2009-06
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Aged
	Animals
	Apoptosis
	Cell Death
	Cell Line
	Cell Survival -- drug effects
	Chromosome Mapping
	Diabetes Mellitus, Type 1 -- genetics
	Genetic Predisposition to Disease
	Humans
	Insulin-Secreting Cells -- cytology -- drug effects -- physiology
	Interferon-gamma -- adverse effects
	Interleukin-1beta -- pharmacology
	Male
	Middle Aged
	Nitric Oxide -- metabolism
	Protein Tyrosine Phosphatase, Non-Receptor Type 2 -- genetics
	RNA, Messenger -- genetics
	RNA, Small Interfering -- genetics
	Rats
	Rats, Wistar
	Recombinant Proteins -- pharmacology
	Tissue Donors
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db08-1510
	info:pii/db08-1510
	info:pmid/19336676
	PMC2682688