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Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

par Andrade Da Cunha, Daniel ;Ladrière, Laurence ;Ortis, Fernanda ;Igoillo Esteve, Mariana ;Gurzov, Esteban Nicolas ;Lupi, Roberto;Marchetti, Piero;Eizirik, Decio ;Cnop, Miriam
Référence Diabetes (New York, N.Y.), 58, 12, page (2851-2862)
Publication Publié, 2009-12

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Titre:	Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
Auteur:	Andrade Da Cunha, Daniel; Ladrière, Laurence; Ortis, Fernanda; Igoillo Esteve, Mariana; Gurzov, Esteban Nicolas; Lupi, Roberto; Marchetti, Piero; Eizirik, Decio; Cnop, Miriam
Informations sur la publication:	Diabetes (New York, N.Y.), 58, 12, page (2851-2862)
Statut de publication:	Publié, 2009-12
Sujet CREF:	Enseignement des sciences
	Biologie
	Biologie moléculaire
	Biologie cellulaire
	Biologie générale
	Diabétologie
	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Antigens, Differentiation -- metabolism
	Apoptosis
	Blotting, Western
	Cell Survival
	Colforsin -- pharmacology
	DNA-Binding Proteins -- metabolism
	Diabetes Mellitus, Type 2 -- metabolism -- prevention & control
	Endoplasmic Reticulum -- metabolism
	Glucagon-Like Peptide 1 -- agonists -- metabolism
	Heat-Shock Proteins -- genetics -- metabolism
	Hypoglycemic Agents -- pharmacology
	Insulin-Secreting Cells -- metabolism
	Lipid Metabolism -- drug effects
	Male
	Peptides -- pharmacology
	Polymerase Chain Reaction
	Proto-Oncogene Proteins -- metabolism
	Proto-Oncogene Proteins c-jun -- genetics -- metabolism
	RNA Interference
	Rats
	Rats, Wistar
	Receptors, Glucagon -- metabolism
	Transcription Factors -- metabolism
	Up-Regulation
	Venoms -- pharmacology
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db09-0685
	info:pii/db09-0685
	info:pmid/19720788
	PMC2780890