Résumé : In healthy subjects, exercise increases cardiac output by 600-900 e.e. per 100 e.e. increase in oxygen consumption. Pulmonary artery pressure hardly changes. In patients with heart failure, increase in cardiac output is smaller, though after compensation figures may approach the normal. Valvular stenosis, mitral as well as pulmonary, reduces in proportion to its severity the increase in cardiac output with exercise. After operation there is often appreciable delay before figures approach the normal. Conditions in constrictive pericarditis arc similar, those in patients with Paget's disease and hyperthyroidism are briefly discussed. © 1958 S. Karger AG, Basel.