par Maris, Calliope 
;D'Haene, Nicky ;Trepant, Anne-Laure ;Le Mercier, Marie ;Sauvage, Sébastien ;Allard, Justine ;Rorive, Sandrine ;Demetter, Pieter ;Decaestecker, Christine ;Salmon, Isabelle
Référence British Journal of Cancer, 113, 5, page (729-737)
Publication Publié, 2015-09
;D'Haene, Nicky ;Trepant, Anne-Laure ;Le Mercier, Marie ;Sauvage, Sébastien ;Allard, Justine ;Rorive, Sandrine ;Demetter, Pieter ;Decaestecker, Christine ;Salmon, Isabelle Référence British Journal of Cancer, 113, 5, page (729-737)
Publication Publié, 2015-09
Article révisé par les pairs
| Résumé : | Glioblastomas (GBMs) are the most common malignant primary brain tumours in adults and are refractory to conventional therapy, including surgical resection, radiotherapy and chemotherapy. The insulin-like growth factor (IGF) system is a complex network that includes ligands (IGFI and IGFII), receptors (IGF-IR and IGF-IIR) and high-affinity binding proteins (IGFBP-1 to IGFBP-6). Many studies have reported a role for the IGF system in the regulation of tumour cell biology. However, the role of this system remains unclear in GBMs. |
