par Soubhye, Jalal 
Président du jury Amighi, Karim
Promoteur Dufrasne, François;Neve, Jean
Publication Non publié, 2013-10-09
Président du jury Amighi, Karim
Promoteur Dufrasne, François
;Neve, Jean Publication Non publié, 2013-10-09
Thèse de doctorat
| Résumé : | The deleterious effects of MPO make it a new target for medicinal research. The aim of our study is to find promising inhibitors of MPO for using them as starting point of new anti-inflammatory drugs. Depending on previous researches on MPO inhibitors, we selected 5-fluorotryptamine as starting compounds. Using docking experiments, we designed a series of compounds derived from 5-fluorotryptamine. Two modifications were proposed: \ |
