par Roufosse, Florence 
;Cogan, Elie ;Goldman, Michel
Référence Annual Review of Medicine, 54, page (169-184)
Publication Publié, 2003
;Cogan, Elie ;Goldman, Michel Référence Annual Review of Medicine, 54, page (169-184)
Publication Publié, 2003
Article révisé par les pairs
| Résumé : | Clinical and biological features of patients with the idiopathic hypereosinophilic syndrome (HES) are heterogeneous. Recent evidence suggests at least two distinct underlying hematological disorders involving myeloid and lymphoid cells, respectively. We therefore suggest that the term idiopathic should be abandoned in the classification of HES. This review defines the "myeloproliferative" and "lymphocytic" variants of the HES and addresses the management of each variant, focusing on diagnosis and treatment of the newly identified lymphocytic variant. |
