par Vokaer, Alain Patrick 
Référence Journal de gynécologie obstétrique et biologie de la reproduction, 2, 5, page (573-588)
Publication Publié, 1973
Référence Journal de gynécologie obstétrique et biologie de la reproduction, 2, 5, page (573-588)
Publication Publié, 1973
Article révisé par les pairs
| Résumé : | The attitude towards prophylaxis and therapy of several generations of clinicians has been influenced by the idea that toxemia of pregnancy results from an abnormal retention of salt and water, which is responsible for edema and an abnormal increase in weight. Neither the overall increase in weight, often underestimated in normal pregnancies, nor the speed of the gain in weight can scientifically be considered as premonitory signs of this disease. Edema by itself, without any sign of other pathology has no poor prognostic significance. It may even appear to be a normal physiological adaptation of the maternal organism to the state of pregnancy. The pathologic physiology of the renin angiotensin aldosterone system during normal pregnancy and abnormal pregnancy is discussed. It seems that the state of pregnancy brings about an increased need for salt and that the pathology of toxemia is accompanied by the exhaustion of the capacity of the kidney and the adrenal cortex to secrete renin. A critical review of the literature does not confirm that either diuretics or the salt free diet is effective in prevention or treatment of toxemia of pregnancy. |
