par Ginsberg, Francis;Famaey, Jean Pierre
Référence Acta rhumatologica, 3, 4, page (286-292)
Publication Publié, 1979
Article révisé par les pairs
Résumé : Efficacy and tolerance of fenbufen were studied in 71 patients suffering from osteoarthritis. A double blind comparison with indomethacin was performed with 46 patients. On the basis of a randomized selection, half of the patients received indomethacin and then fenbufen and half of the patients received fenbufen first and then indomethacin. A six months open trial was performed by 25 patients. The efficacy of fenbufen was better than that of indomethacin for two studied parameters and the equivalent for the others. Side-effects with fenbufen were not statistically different from those obtained with indomethacin. Tolerance and efficacy were also very satisfactory during the long term open trial.