par Beten, D.;Moes, André Jules 
;Van Gansbeke, Bernard ;Schoutens, André
Référence International journal of pharmaceutics, 123, 1, page (145-147)
Publication Publié, 1995-08
;Van Gansbeke, Bernard ;Schoutens, André Référence International journal of pharmaceutics, 123, 1, page (145-147)
Publication Publié, 1995-08
Article révisé par les pairs
| Résumé : | The gastric emptying half-times of Eudragit® S-111 In-oxinate coevaporate particles (fraction size, 0.10-0.50 mm; density, 1.36 g cm-3) were determined by gamma scintigraphy in both fasted and fed healthy volunteers. The mean gastric emptying half-times ± SD under fasting and non-fasting conditions were 67 ± 15 and 308 ± 53 min, respectively, indicating that gastric emptying of coevaporate particles is delayed in the presence of food to a greater extent than most pellets of normal density. © 1995. |
