Sustained viral suppression and higher CD4+ T-cell count reduces the risk of persistent cervical high-risk human papillomavirus infection in HIV-positive women

Konopnicki, Deborah; Manigart, Yannick; Gilles, Christine; Barlow, Patricia; de Marchin, Jérôme; Feoli, Francesco; Larsimont, Denis; Delforge, Marc; De Wit, Stéphane; Clumeck, Nathan

doi:doi/10.1093/infdis/jit090

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Sustained viral suppression and higher CD4+ T-cell count reduces the risk of persistent cervical high-risk human papillomavirus infection in HIV-positive women

par Konopnicki, Deborah

;Manigart, Yannick

;Gilles, Christine

;Barlow, Patricia

;de Marchin, Jérôme ;Feoli, Francesco

;Larsimont, Denis

;Delforge, Marc ;De Wit, Stéphane

;Clumeck, Nathan

Référence The Journal of infectious diseases, 207, 11, page (1723-1729)
Publication Publié, 2013-06

Article révisé par les pairs

Résumé :

Studies analyzing the impact of combination antiretroviral therapy (cART) on cervical infection with high-risk human papillomavirus (HR-HPV) have generated conflicting results. We assessed the long-term impact of cART on persistent cervical HR-HPV infection in a very large cohort of 652 women who underwent follow-up of HIV infection for a median duration of 104 months.

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