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Levels of gastrin-cholecystokinin-like immunoreactivity in the brains of genetically obese and non-obese rats

par Finkelstein, Judith J.A.;Steggles, Alan A.W.;Lotstra, Françoise ;Vanderhaeghen, Jean-Jacques
Référence Peptides, 2, 1, page (19-21)
Publication Publié, 1981

Article révisé par les pairs

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Résumé :

Levels of gastrin-cholecystokinin-like immunoreactivity were measured in three brain regions (cortex, diencephalon, brainstem) and the pituitary gland in groups of genetically obese Zucker rats and their non-obese littermates. The obese animals had significantly increased body weights and significantly lowered brain weights. However, levels of gastrin-cholecystokinin-like immunoreactivity were not different between the two groups in any of the regions measured. These results contrast with a recent report [11] in which ob/ob mice were found to have decreased levels of cholecystokinin in their brains. © 1981 ANKHO International Inc.