par Lemaire, Muriel ;Preiser, Jean-Charles
Référence Nutrition clinique et métabolisme, 28, 4, page (294-300)
Publication Publié, 2014-12
Article révisé par les pairs
Résumé : Intensive care unit-acquired muscular weakness is a common and multifactorial complication of the critically ill patient. Clinical signs and long-term consequences can worsen the vital outcome and functional autonomy. The pathophysiology of this condition is complex and partially iatrogenic, when prolonged sedation is used. The screening, prevention and treatment of muscular weakness require a multimodal approach, combining early mobilization, shortening of sedation and optimal proteo-caloric intakes, avoiding overfeeding during the early phase and underfeeding during the late phase of critical illness.