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Oral contraception can decrease the pituitary capacity to release gonadotrophins in response to synthetic LH-releasing-hormone

par Robyn, Claude ;Schöndorf, H.;Jürgensen, Ortrun;Sioe Eng Dericks-Tan, J.;Taubert, Hans Dieter
Référence Archiv für Gynäkologie, 216, 1, page (73-80)
Publication Publié, 1973-03

Article révisé par les pairs

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Résumé :

The amounts of luteinizing hormone (LH) and follicle stimulating hormone (FSH) released in response to the intravenous administration of 12.5, 25, and 100 μg of LH-Releasing Hormone (LH-RH) were found to be severely impeded in 4 out of 5 women who had been taking oral contraceptives for periods ranging from 12 to 36 months. Long-term administration of oral contraceptives seems to limit the reserve capacity of the pituitary to release gonadotrophins. © 1974 J. F. Bergmann.