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Prise en charge de la douleur au cours des procédures invasives en cancérologie : efficacité et acceptabilité du mélange inhalé 50 % N2O/O2 (MEOPA)

par Krakowski, Ivan;Baylot, Denis;Freyssinet-Durand, C.;Chvetzoff, Gisèle;Collin, Élisabeth E.;Feuvret, Loïc;Coulouma, Rémi;Dixmerias, Florence;Lauwers-Allot, Elisabeth;Lossignol, Dominique ;Billoët, Catherine
Référence Douleur et analgésie, 23, 2, page (113-120)
Publication Publié, 2010-06

Article révisé par les pairs

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Résumé :

Inhaled 50% N2O/O2 premix efficacy and safety, in addition to usual treatment, during painful procedures in oncology, was evaluated in a double-blind randomised study performed in patients ≥18 years. Initial and maximum pain during the procedure experienced by the patient was assessed using a visual analogical scale (VAS). Thirty percent of 199 patients suffered from a permanent background pain. Maximum pain felt by the patients during the invasive procedure was 10 mm lower in the 50% N2O/O 2 premix group vs the placebo group (p < 0.01). Feasibility by patient and medical team was greater than 89%. This study shows that administration of 50% N2O/O2 premix is an efficient, well-tolerated complement with good feasibility, according to the patient and medical team. © 2010 Médecine et Hygiène et Springer-Verlag France.