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Cord serum prolactin in relation to the time of the day, the sex of the neonate and the birth weight

par Badawi, M;Van Exter, Camille ;Desnoeck, Josiane Bertha ;Van Meenen, François ;Robyn, Claude
Référence Acta endocrinologica (Print ed.), 87, 2, page (241-247)
Publication Publié, 1978

Article révisé par les pairs

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Résumé :

Serum prolactin was measured in 581 blood samples collected immediately after birth from 568 single new-born and from 9 pairs of twins. Cord serum prolactin is high at birth: the mean level is some 5 times higher than in adults. There is no sex difference in cord serum prolactin concentration in the neonate. Mean serum prolactin is significantly higher at 1.00 and 2.00 a.m. Thus a circadian periodicity in serum prolactin concentration seems to appear already during foetal life well before the organization of sleep rhythm. Cord serum prolactin increases with birth weight ranging from 1500 g to 3500 g. Thus, the control of levels of circulating prolactin changes during foetal life resulting in a progressive increase starting from mid-pregnancy. Mean cord serum prolactin at birth is lower in twins than in single new-borns. There is no significant difference in serum prolactin between the first and second twin.