par Attig, Ezzedine;Capon, André 
;Demeurisse, Guy ;Verhas, Michel
Référence Stroke, 21, 11, page (1555-1561)
Publication Publié, 1990
;Demeurisse, Guy ;Verhas, Michel Référence Stroke, 21, 11, page (1555-1561)
Publication Publié, 1990
Article révisé par les pairs
| Résumé : | We measured regional cerebral blood flow using the xenon-133 inhalation method, at approximately 1 month after onset, in 60 stroke patients who had no evidence of major carotid artery stenosis or occlusion. Their single lesions (43 infarcts and 17 hematomas) were located in the capsulothalamolenticular region, sparing the cortex. Hemispheric mean cerebral blood flow was reduced on the side of the lesion in 25 patients and on both sides in 20. Regional hypoperfusion was observed in 46 patients (ipsilaterally in 34, bilaterally in 10, and contralaterally in two). Regional hypoperfusion was observed most frequently in the frontal lobe, particularly in the motor and premotor cortices of the prerolandic area. The 46 patients with regional hypoperfusion were compared with the 14 patients without regional hypoperfusion, considering the size and location of the lesion as well as the functional and analytic motor performances. As as rule, the lesion was slightly smaller and more posterior and the functional (p<0.001) and analytic (p<0.05) motor performances were significantly better in the 14 patients without regional hypoperfusion. Since the xenon-133 inhalation method examines cortical blood flow, we can attribute blood flow reductions resulting from deep-seated lesions to a functional depression akin to diachisis. Interpretation of the clinical consequences and pathogenesis of this phenomenon requires further sequential and pathologic studies. |
