par Englebienne, Patrick;Verhas, Michel ;Van Hoonacker, Anne;Khlebtsov, Nikolai Grigor Evich N.G.
Référence Combinatorial chemistry & high throughput screening, 6, 8, page (777-787)
Publication Publié, 2003-12
Référence Combinatorial chemistry & high throughput screening, 6, 8, page (777-787)
Publication Publié, 2003-12
Article révisé par les pairs
Résumé : | The post-genomic era is revolutionizing the drug discovery process. The new challenges in the identification of therapeutic targets require efficient technological tools in order to be properly addressed. Label-free detection systems use proteins or ligands coupled to materials of which the physical properties are measurably modified upon specific interactions. Among the label-free systems currently available, the use of metal nanocolloids offers enhanced throughput and flexibility for real-time biomolecular recognition monitoring at a reasonable cost. |