par Six, Roland;Leclercq, Raoul 
;Noeninckx, Frederik
Référence Acta clinica Belgica (Ed. multilingue), 27, 1-2, page (426-434)
Publication Publié, 1972
;Noeninckx, Frederik Référence Acta clinica Belgica (Ed. multilingue), 27, 1-2, page (426-434)
Publication Publié, 1972
Article révisé par les pairs
| Résumé : | An adrenocortical carcinoma in a 54 year old female patient is reported. Arterial hypertension, muscular weakness, hypokalemic alkalosis and urinary potassium loss were the prominent features. Although plasma corticol was increased, there were no clinical signs of hypercortisolism. Surgical removal of the tumor appeared to be impossible; the insecticide o p ' DDD therapy achieved temporary normalization of the urinary excretion not only of 17 hydroxycorticoids and of 17 ketosteroids but also of tetrahydroaldosterone. The pathogenesis of the mineralocorticoid syndrome and the influence of o p ' DDD on the adrenocortical aldosterone production are discussed. |
