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Labour analgesia in a patient with carnitine palmityl transferase deficiency and idiopathic thrombocytopenic purpura

par Mardirosoff, Chahé;Dumont, Lionel ;Cobin, Laurence;Massaut, Jacques
Référence International journal of obstetric anesthesia, 7, 2, page (134-136)
Publication Publié, 1998-04

Article révisé par les pairs

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Résumé :

We report a case of a woman with carnitine palmityl deficiency (CPT) and idiopathic thrombocytopenic purpura, presenting in active labour at 38 weeks gestation. We discuss different anaesthetic factors involved with both diseases, and we propose an optimal management of such cases. Neuraxial analgesia with minimal motor blockade is indicated in early labour because it is necessary to alleviate stress in order to avoid rhabdomyolisis associated with CPT deficiency. Neuraxial analgesia is also needed because the theoretical risk of performing a caesarean section is higher than in a normal population, first because labour must be kept as short as possible and secondly because the possible thrombocytopenia in the baby precludes the use of instrumental delivery.