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The metabolic consequences of sleep deprivation

par Knutson, Kristen K.L.;Spiegel, Karine ;Penev, Plamen;Van Cauter, Eve
Référence Sleep medicine reviews, 11, 3, page (163-178)
Publication Publié, 2007-06

Article révisé par les pairs

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Résumé :

The prevalence of diabetes and obesity is increasing at an alarming rate worldwide, and the causes of this pandemic are not fully understood. Chronic sleep curtailment is a behavior that has developed over the past 2-3 decades. Laboratory and epidemiological studies suggest that sleep loss may play a role in the increased prevalence of diabetes and/or obesity. Current data suggest the relationship between sleep restriction, weight gain and diabetes risk may involve at least three pathways: (1) alterations in glucose metabolism; (2) upregulation of appetite; and (3) decreased energy expenditure. The present article reviews the current evidence in support of these three mechanisms that might link short sleep and increased obesity and diabetes risk. © 2007 Elsevier Ltd. All rights reserved.