par Fowkes, Francis Gerald;Murray, Gordon;Butcher, Isabella;Folsom, Aaron;Hirsch, A.T.;Couper, David;Debacker, Guy;Kornitzer, Marcel ;Newman, Anne;Sutton-Tyrrell, Kim;Cushman, M.;Lee, A.J.;Price, Jackie;D'Agostino, Ralph;Murabito, Joanne;Norman, Paul;Masaki, K.H.;Bouter, Lex;Heine, R.J.;Stehouwer, Coen DA Coen;McDermott, Mary McGrae;Stoffers, Henri Ejh;Knottnerus, Johannes André;Ogren, Mats;Hedblad, Bo;Koenig, Wolfgang;Meisinger, Christa;Cauley, Jane A.;Franco, Oscar;Hunink, Myriam;Hofman, Albert;Witteman, Jacqueline;Criqui, Michael;Langer, R.D.;Hiatt, William Robert;Hamman, Richard
Référence European journal of preventive cardiology, 21, 3, page (310-320)
Publication Publié, 2014-03
Référence European journal of preventive cardiology, 21, 3, page (310-320)
Publication Publié, 2014-03
Article révisé par les pairs
Résumé : | Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events. © 2013 The European Society of Cardiology. |