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Robust nonlinear state estimation of bioreactors based on H∞ hybrid observers

par Bogaerts, Philippe ;Coutinho, Daniel Ferreira
Référence Computers & chemical engineering, 60, page (315-328)
Publication Publié, 2014-01

Article révisé par les pairs

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Résumé :

This paper proposes a robust nonlinear observer for bioreactors combining the classical asymptotic observer and a nonlinear Luenberger-like observer. The resulting hybrid observer considers a new definition of the hybridization parameter which reflects the kinetic model confidence. The nonlinear observer is tuned on the basis of robust H-infinity approach and the differential-algebraic representation (DAR) of nonlinear systems. A simulated case study concerning fed-batch animal cell cultures is presented to demonstrate the potentials and advantages of the proposed approach for state estimation of bioreactors. © 2013 Elsevier Ltd.