par Piagnerelli, Michaël ;Lejeune, P.;Vanhaeverbeek, Michel
Référence Acta clinica Belgica (Ed. multilingue), 54, 6, page (351-356)
Publication Publié, 1999-12
Article révisé par les pairs
Résumé : Ethylene glycol intoxication is a rare but dangerous type of poisoning. It causes a severe acidosis with high anion and osmolal gaps. Clinical manifestations of the ethylene glycol intoxication can be divided in three phases: a neurologic stage, with hallucinations, stupor and coma; the second stage is cardiovascular with cardiac failure. Renal failure characterizes the third stage, due to acute tubular necrosis. After aggressive gastric emptying, the main treatment is ethanol or 4-methypyrazole, which can be given either orally or intravenous, with supportive measures for all symptoms or diseased organ.