par Errera, Maurice Leo
Référence International journal of radiation oncology, biology, physics, 5, 7, page (1077-1083)
Publication Publié, 1979
Article révisé par les pairs
Résumé : Sensitivity of DNA to external agents (physical as well as chemical) has become complex and research has led to the discovery of several often related repair pathways. Unrepair or misrepair of damage to DNA may be lethal or mutagenic to cells (error prone repair) and in mammals initiate tumors. It has become difficult, if not impossible, to dissociate the analysis of DNA repair from that of replication and recombination and it is becoming more and more apparent that the study of repair in microorganisms contributes in a decisive way to the understanding of many late effects of radiation or chemicals in higher organisms, including cancer.