Donepezil in the treatment of mild to moderate Alzheimer's disease: Report of a Belgian multicenter study

Santens, Patrick; Ventura, Manfredi

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Donepezil in the treatment of mild to moderate Alzheimer's disease: Report of a Belgian multicenter study

par Santens, Patrick ;Ventura, Manfredi

Référence Acta neurologica belgica, 103, 3, page (159-163)
Publication Publié, 2003-09

Article révisé par les pairs

Résumé :

In this report the results of a Belgian multicenter 24-week open-label study with donepezil in the treatment of mild to moderate Alzheimer's disease are described. Efficacy and safety were evaluated in a sample of 200 patients recruited in 25 Belgian centers. No significant changes could be found in cognition and behaviour over this 6-month period. Changes in daily functioning were small. Safety data were comparable to those reported in international trials. These results suggest that the findings of more robust double-blind, placebo-controlled studies can be confirmed in real life situations.

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