par Bastenie, Paul Auguste ;Bonnyns, Marc ;Vanhaelst, Luc
Référence The American journal of medicine, 79, 1, page (91-100)
Publication Publié, 1985
Article révisé par les pairs
Résumé : It is generally admitted that primary myxedema in adults is the outcome of autoimmune atrophic thyroiditis. The present review traces the natural history of this process from its incipient biologic and genetic anomalies up to its protracted asymptomatic course, clinical development, and eventual lethal complications. The apprehension of preclinical hypothyroidism may change a clinician's outlook on early diagnosis and therapy.