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Natural history of primary myxedema

par Bastenie, Paul Auguste ;Bonnyns, Marc ;Vanhaelst, Luc
Référence The American journal of medicine, 79, 1, page (91-100)
Publication Publié, 1985

Article révisé par les pairs

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Résumé :

It is generally admitted that primary myxedema in adults is the outcome of autoimmune atrophic thyroiditis. The present review traces the natural history of this process from its incipient biologic and genetic anomalies up to its protracted asymptomatic course, clinical development, and eventual lethal complications. The apprehension of preclinical hypothyroidism may change a clinician's outlook on early diagnosis and therapy.