Article révisé par les pairs
Résumé : A 1,500 Cal test meal was used to study in man the apoprotein B-carbohydrate content and composition of VLDL, IDL and LDL in relation to the variation of plasma lipids and lipoproteins and the VLDL-apoprotein composition. Three essential facts emerge from the study: the mirror image (inverse significant correlation) between VLDL-apo B plasma concentration and N-acetylglucosamine content of apo B; a reduction in total carbohydrate concentration of VLDL- and LDL-apo B, 2-4 h after the test meal and a trend to a reduction in the mannose content; a significant correlation between sialic acid and apoprotein B concentration in plasma LDL during fasting. The effect of diet and subsequent fasting on carbohydrates of lipoproteins and the consequence of such changes on lipoprotein uptake are briefly discussed.