par Plenevaux, Alain;Lemaire, Christian;Aerts, Joël;Lacan, Goran;Rubins, Daniel;Melega, William;Brihaye, Claude
;Degueldre, Christian;Fuchs, Sonia;Salmon, Eric;Maquet, Pierre;Laureys, Steven;Damhaut, Philippe;Weissmann, Dinah;Le Bars, D.;Pujol, Jean François;Luxen, André 
Référence Nuclear medicine and biology, 27, 5, page (467-471)
Publication Publié, 2000-07


Référence Nuclear medicine and biology, 27, 5, page (467-471)
Publication Publié, 2000-07
Article révisé par les pairs
Résumé : | This paper summarizes the present status of the researches conducted with [18F]4-(2'-methoxyphenyl)-1-[2'-[N-(2''-pyridinyl)-p- fluorobenzamido]ethyl]-piperazine known as [18F]p-MPPF, a new 5-HT(1A) antagonist for the study of the serotonergic neurotransmission with positron emission tomography (PET). This includes chemistry, radiochemistry, animal data (rats, cats, and monkeys) with autoradiography and PET, human data with PET, toxicity, and metabolism. (C) 2000 Elsevier Science Inc. |