par Toussaint, Dominique ;Danis, Pierre
Référence American journal of ophthalmology, 72, 2, page (342-347)
Publication Publié, 1971-08
Article révisé par les pairs
Résumé : The ocular histopathologic abnormalities are reviewed in a 44-year-old woman with Refsum's syndrome who was blind and deaf and had polyneuritis, cataracts, and retinitis pigmentosa. The most noteworthy abnormality in the ocular tissues was the presence of sudanophilic material in the sclera, trabecular meshwork, iris muscles, and most especially, a coating of the retinal pigment epithelium with fat. It is suggested that this accumulation of lipid interfered with the normal generation of retinal, resulting in degeneration of the photoreceptors. © 1971.