Article révisé par les pairs
Titre:
  • Cytokines tumor necrosis factor-alpha and interferon-gamma induce pancreatic beta-cell apoptosis through STAT1-mediated Bim protein activation.
Auteur:Barthson, Jenny; Germano, Carla Maria Ramos C.M.; Moore, Fabrice; Maida, Adriano; Drucker, Daniel J; Marchetti, Piero; Gysemans, Conny; Mathieu, Chantal; Nuñez, Gabriel; Jurisicova, Andrea; Eizirik, Decio L.; Gurzov, Esteban Nicolas
Informations sur la publication:The Journal of biological chemistry, 286, 45, page (39632-39643)
Statut de publication:Publié, 2011
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adult
Aged
Animals
Antiviral Agents -- metabolism -- pharmacology
Apoptosis -- drug effects -- physiology
Apoptosis Regulatory Proteins -- genetics -- metabolism
Cells, Cultured
Female
Gene Expression Regulation -- drug effects -- physiology
Gene Silencing
Humans
Insulin-Secreting Cells -- metabolism
Interferon-gamma -- genetics -- metabolism -- pharmacology
Male
Membrane Proteins -- genetics -- metabolism
Mice
Mice, Knockout
Middle Aged
Neuropeptides -- genetics -- metabolism
Proto-Oncogene Proteins -- genetics -- metabolism
STAT1 Transcription Factor -- genetics -- metabolism
Tumor Necrosis Factor-alpha -- genetics -- metabolism -- pharmacology
Tumor Suppressor Protein p53 -- genetics -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M111.253591
info:pii/M111.253591
info:scp/80655144735
info:pmid/21937453
PMC3234786

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