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Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.

par Igoillo Esteve, Mariana ;Marselli, L;Andrade Da Cunha, Daniel ;Ladrière, Laurence ;Ortis, Fernanda ;Grieco, Fabio Arturo ;Dotta, F;Weir, G.;Marchetti, Piero;Eizirik, Decio L. ;Cnop, Miriam
Référence Diabetologia, 53, 7, page (1395-1405)
Publication Publié, 2010

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Titre:	Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.
Auteur:	Igoillo Esteve, Mariana; Marselli, L; Andrade Da Cunha, Daniel; Ladrière, Laurence; Ortis, Fernanda; Grieco, Fabio Arturo; Dotta, F; Weir, G.; Marchetti, Piero; Eizirik, Decio L.; Cnop, Miriam
Informations sur la publication:	Diabetologia, 53, 7, page (1395-1405)
Statut de publication:	Publié, 2010
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Chemokine
	Cytokine
	Endoplasmic reticulum
	Fatty acid
	Inflammation
	Interleukin-1β
	Islet
	Palmitate
	Pancreatic beta cell
	Type 2 diabetes
MeSH keywords:	Aged
	Cell Line
	Chemokine CCL2 -- metabolism
	Chemokine CXCL1
	Diabetes Mellitus, Type 2 -- metabolism
	Enzyme-Linked Immunosorbent Assay
	Female
	Fluorescent Antibody Technique
	Humans
	Insulin-Secreting Cells -- metabolism
	Interleukin-6 -- metabolism
	Interleukin-8 -- metabolism
	Islets of Langerhans -- drug effects -- metabolism
	Male
	Middle Aged
	NF-kappa B -- metabolism
	Oligonucleotide Array Sequence Analysis
	Palmitates -- pharmacology
	Polymerase Chain Reaction
	Radioimmunoassay
	Tumor Necrosis Factor-alpha -- metabolism
Note générale:	In Vitro
	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-010-1707-y
	info:scp/77955658618
	info:pmid/20369226