Article révisé par les pairs
Titre:
  • TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.
Auteur:Győrffy, Balázs; Bottai, Giulia; Lehmann-Che, Jacqueline; Kéri, György; Orfi, László; Iwamoto, Takayuki; Desmedt, Christine; Bianchini, Giampaolo; Turner, Nicholas C; de Thé, Hugues; Andre, Fabrice; Sotiriou, Christos; Hortobagyi, Gabriel N.; Di Leo, Angelo; Pusztai, Lajos; Santarpia, Libero
Informations sur la publication:Molecular Oncology, 8, 3, page (508-19)
Statut de publication:Publié, 2014-05
Sujet CREF:Cancérologie
Médecine pathologie humaine
Mots-clés:Breast cancer subtypes
Chemotherapy
MPS1 protein kinase
SP600125
TP53 mutation status
Tumor relapse
MeSH keywords:Anthracenes -- pharmacology
Breast -- drug effects -- metabolism -- pathology
Breast Neoplasms -- diagnosis -- drug therapy -- genetics -- pathology
Cell Cycle Proteins -- antagonists & inhibitors -- genetics
Cell Line, Tumor
Cell Survival
Female
Genes, p53
Humans
Mutation
Neoplasm Recurrence, Local -- diagnosis -- drug therapy -- genetics -- pathology
Prognosis
Protein-Serine-Threonine Kinases -- antagonists & inhibitors -- genetics
Protein-Tyrosine Kinases -- antagonists & inhibitors -- genetics
Survival Analysis
Tumor Suppressor Protein p53 -- genetics
Note générale:JOURNAL ARTICLE
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1574-7891
info:doi/10.1016/j.molonc.2013.12.018
info:pii/S1574-7891(13)00190-7
info:scp/84899488362
info:pmid/24462521

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