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Variability of insulin sensitivity during the first 4 days of critical illness: implications for tight glycemic control.

par Pretty, Christopher G;Le Compte, Aaron;Chase, James Geoffrey;Shaw, G;Preiser, Jean-Charles ;Penning, Sophie;Desaive, Thomas
Référence Annals of intensive care, 2, 1, page (17)
Publication Publié, 2012

Article révisé par les pairs

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Résumé :

Effective tight glycemic control (TGC) can improve outcomes in critical care patients, but it is difficult to achieve consistently. Insulin sensitivity defines the metabolic balance between insulin concentration and insulin-mediated glucose disposal. Hence, variability of insulin sensitivity can cause variable glycemia. This study quantifies and compares the daily evolution of insulin sensitivity level and variability for critical care patients receiving TGC.