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RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.

par Cnop, Miriam ;Abdulkarim, Baroj ;Bottu, Guy ;Andrade Da Cunha, Daniel ;Igoillo Esteve, Mariana ;Masini, Matilde;Turatsinze, Jean Valéry ;Griebel, Thasso;Villate, Olatz ;Santin Gomez, Izortze ;Bugliani, Marco;Ladrière, Laurence ;Marselli, Lorella;McCarthy, Mark I;Marchetti, Piero;Sammeth, Michael;Eizirik, Decio L.
Référence Diabetes (New York, N.Y.), 63, page (1978-93)
Publication Publié, 2014

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Titre:	RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Auteur:	Cnop, Miriam; Abdulkarim, Baroj; Bottu, Guy; Andrade Da Cunha, Daniel; Igoillo Esteve, Mariana; Masini, Matilde; Turatsinze, Jean Valéry; Griebel, Thasso; Villate, Olatz; Santin Gomez, Izortze; Bugliani, Marco; Ladrière, Laurence; Marselli, Lorella; McCarthy, Mark I; Marchetti, Piero; Sammeth, Michael; Eizirik, Decio L.
Informations sur la publication:	Diabetes (New York, N.Y.), 63, page (1978-93)
Statut de publication:	Publié, 2014
Sujet CREF:	Biologie
	Biologie moléculaire
	Biologie cellulaire
	Biologie générale
	Diabétologie
MeSH keywords:	Animals
	Apoptosis -- drug effects -- genetics
	Blotting, Western
	Cell Line
	Cells, Cultured
	Diabetes Mellitus, Type 2 -- genetics -- metabolism
	Endoplasmic Reticulum Stress -- drug effects -- genetics
	Female
	Gene Expression Regulation, Enzymologic
	Genetic Predisposition to Disease
	Humans
	Inflammation -- genetics -- metabolism
	Islets of Langerhans -- drug effects -- metabolism
	Male
	Palmitates -- metabolism
	Sequence Analysis, RNA
	Signal Transduction
	Transcriptome
Note générale:	JOURNAL ARTICLE
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db13-1383
	info:pii/db13-1383
	info:scp/84900334812
	info:pmid/24379348