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Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.

par Reschner, Anca;Bontems, S.;Le Gac, Stéphane ;Lambermont, Javiera ;Marcelis, Lionel ;Defrancq, Eric;Moucheron, Cécile ;Kirsch-De Mesmaeker, Andrée ;Raes, Martine;Piette, Jacques;Delvenne, Philippe O
Référence Gene therapy, 20, 4, page (435-443)
Publication Publié, 2013

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Titre:	Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.
Auteur:	Reschner, Anca; Bontems, S.; Le Gac, Stéphane; Lambermont, Javiera; Marcelis, Lionel; Defrancq, Eric; Moucheron, Cécile; Kirsch-De Mesmaeker, Andrée; Raes, Martine; Piette, Jacques; Delvenne, Philippe O
Informations sur la publication:	Gene therapy, 20, 4, page (435-443)
Statut de publication:	Publié, 2013
Sujet CREF:	Photochimie
Mots-clés:	antisense therapy
	carcinoma
	oligonucleotides
	photoreactive complex
	phototherapy
	ruthenium
MeSH keywords:	Cell Line, Tumor
	Cell Proliferation -- drug effects
	Cross-Linking Reagents -- chemistry
	Female
	Gene Silencing
	Genes, p53
	Genetic Therapy
	Humans
	Light
	Oligonucleotides -- chemistry -- genetics
	Oncogene Proteins, Viral -- genetics -- metabolism
	Repressor Proteins -- genetics -- metabolism
	Ruthenium Compounds -- chemistry -- radiation effects
	Tumor Suppressor Protein p53 -- metabolism
	Uterine Cervical Neoplasms -- therapy -- virology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0969-7128
	info:doi/10.1038/gt.2012.54
	info:pii/gt201254
	info:scp/84875919097
	info:pmid/22809997