Titre:
  • Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.
Auteur:Stygelbout, Virginie; Leroy, Karelle; Pouillon, Valérie; Ando, Kunie; D'Amico, Eva; Jia, Yonghui; Luo, Hongwen; Duyckaerts, Charles; Erneux, Christophe; Schurmans, Stéphane; Brion, Jean Pierre
Informations sur la publication:Brain, 137, page (537-552)
Statut de publication:Publié, 2014-01
Sujet CREF:Pathologie générale
Sciences biomédicales en général
Histologie
Sciences bio-médicales et agricoles
Mots-clés:Alzheimer pathology
inositol (1,3,4,5) tetrakisphosphate
inositol phosphates
ITPKB
MeSH keywords:Aged
Aged, 80 and over
Alzheimer Disease -- enzymology -- pathology
Animals
Apoptosis -- physiology
Brain -- enzymology -- pathology
Cell Line, Tumor
Female
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Middle Aged
Neurites -- pathology
Neuroblastoma -- enzymology -- pathology
Phosphotransferases (Alcohol Group Acceptor) -- biosynthesis -- physiology
Plaque, Amyloid -- pathology
Note générale:JOURNAL ARTICLE
SCOPUS: ar.j
Langue:Autre
Identificateurs:urn:issn:0006-8950
info:doi/10.1093/brain/awt344
info:pii/awt344
info:scp/84893828779
info:pmid/24401760