par Goldman, Michel ;Liesnard, Corinne ;Vanherweghem, Jean-Louis ;Dolle, Nicole;Toussaint, Charles ;Sprecher-Goldberger, Suzanne;Cogniaux, Jacqueline;Thiry, Lise
Référence British medical journal (Clinical research ed.), 293, page (161-162)
Publication Publié, 1986
Référence British medical journal (Clinical research ed.), 293, page (161-162)
Publication Publié, 1986
Article révisé par les pairs
Résumé : | Patients and members of staff from a haemodialysis unit were tested for markers of infection with human T cell lymphotropic virus type III (HTLV-III), the virus associated with the acquired immune deficiency syndrome (AIDS). An enzyme linked immunosorbent assay showed eight of 100 patients to have antibodies to HTLV-III. In five of these patients past or present infection with HTLV-III was confirmed by Western blot analysis or detection of HTLV-III antigens in lymphocyte cultures, or both. Investigation of other risk factors for AIDS showed that the putative source of HTLV-III was unrelated to dialysis in two patients whereas blood transfusion was the most likely cause of contamination in the others. No member of staff gave a positive result in the enzyme linked immunosorbent assay. Nosocomial transmission of HTLV-III seems unlikely if precautions similar to those recommended for the control of hepatitis B infection are applied. |