par Abeloos, Laurence ;Lefranc, Florence
Référence Clinical chemistry and laboratory medicine, 49, 6, page (971-975)
Publication Publié, 2011-06
Article révisé par les pairs
Résumé : Predicting which meningiomas will recur and which will not is clinically important, and still represents a major clinical challenge. A number of different molecular, genetic, and/or biochemical markers involved in cell proliferation, invasion, angiogenesis, and cell transformation have been investigated in attempts to predict the risk of post-surgical meningioma recurrence. In this short review we emphasize what has actually been accomplished in this area. Finally, we highlight the potential of S100 serum protein concentrations as a prognostic factor predicting meningioma recurrence. We conclude that serum concentrations of S100 group proteins may prove to be useful as prognostic markers and suggest further pros-pective trials be done. © 2011 by Walter de Gruyter Berlin Boston.