par Goyens, Philippe 
;Brasseur, Daniel ;Cadranel, Samy
Référence Journal of pediatric gastroenterology and nutrition, 4, 4, page (677-680)
Publication Publié, 1985-08
;Brasseur, Daniel ;Cadranel, Samy Référence Journal of pediatric gastroenterology and nutrition, 4, 4, page (677-680)
Publication Publié, 1985-08
Article révisé par les pairs
| Résumé : | Celiac disease was diagnosed in two unrelated infants aged 7 and 7.5 months with severe malnutrition. They showed typical clinical, biological, and histological signs of the disease. Moreover, accompanying copper deficiency was suggested by severe hypocupremia and persistent neutropenia; bone radiographs were also compatible with this diagnosis. Rapid and complete correction of these anomalies could only be obtained after addition of oral copper sulfate to the gluten-free diet. Mechanisms possibly involved in the development of copper deficiency in young infants with celiac disease are: chronic malabsorption; high copper needs in rapidly growing infants; and possibly increased biliary and digestive losses. It is therefore suggested that young children with severe celiac disease should be monitored for their copper status. |
