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PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer.

par Loi, Sherene ;Michiels, Stefan ;Baselga, José;Bartlett, John M S;Singhal, Sandeep K;Sabine, Vicky S;Sims, Andrew H;Sahmoud, Tarek;Dixon, J Michael;Piccart-Gebhart, Martine ;Sotiriou, Christos
Référence PloS one, 8, 1, page (e53292)
Publication Publié, 2013

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Titre:	PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer.
Auteur:	Loi, Sherene; Michiels, Stefan; Baselga, José; Bartlett, John M S; Singhal, Sandeep K; Sabine, Vicky S; Sims, Andrew H; Sahmoud, Tarek; Dixon, J Michael; Piccart-Gebhart, Martine; Sotiriou, Christos
Informations sur la publication:	PloS one, 8, 1, page (e53292)
Statut de publication:	Publié, 2013
Sujet CREF:	Cancérologie
	Sciences biomédicales
MeSH keywords:	Aged
	Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
	Breast Neoplasms -- genetics -- metabolism
	Cell Proliferation
	Female
	Gene Expression Regulation, Neoplastic
	Genotype
	Humans
	Middle Aged
	Mutation
	Nitriles -- administration & dosage
	Phosphatidylinositol 3-Kinases -- genetics
	Receptors, Estrogen -- metabolism
	Sirolimus -- administration & dosage -- analogs & derivatives
	TOR Serine-Threonine Kinases -- metabolism
	Triazoles -- administration & dosage
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1932-6203
	info:doi/10.1371/journal.pone.0053292
	info:pii/PONE-D-12-14015
	info:scp/84871820669
	info:pmid/23301057
	PMC3534682