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GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim

par Nogueira, Tatiane C;Paula, Flavia M.;Villate, Olatz ;Colli, Maikel Luis ;Moura, Rodrigo F;Andrade Da Cunha, Daniel ;Marselli, Lorella;Marchetti, Piero;Cnop, Miriam ;Julier, Cécile;Eizirik, Decio L.
Référence PLOS genetics, 9, 5, e1003532
Publication Publié, 2013

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Titre:	GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
Auteur:	Nogueira, Tatiane C; Paula, Flavia M.; Villate, Olatz; Colli, Maikel Luis; Moura, Rodrigo F; Andrade Da Cunha, Daniel; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Julier, Cécile; Eizirik, Decio L.
Informations sur la publication:	PLOS genetics, 9, 5, e1003532
Statut de publication:	Publié, 2013
Sujet CREF:	Médecine clinique [biologie clinique]
MeSH keywords:	Aged
	Alternative Splicing -- genetics
	Animals
	Apoptosis -- genetics
	Apoptosis Regulatory Proteins -- genetics -- metabolism
	Diabetes Mellitus, Type 1 -- etiology -- genetics
	Diabetes Mellitus, Type 2 -- etiology -- genetics
	Female
	Gene Knockdown Techniques
	Humans
	Insulin -- genetics
	Insulin-Secreting Cells -- metabolism -- pathology
	Male
	Membrane Proteins -- genetics -- metabolism
	Mice
	Middle Aged
	Protein Isoforms -- genetics
	Proto-Oncogene Proteins -- genetics -- metabolism
	Rats
	Transcription Factors -- genetics
Note générale:	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1553-7390
	info:doi/10.1371/journal.pgen.1003532
	info:pii/PGENETICS-D-12-02709
	info:scp/84878507398
	info:pmid/23737756
	PMC3667755