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Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial.

par Dutton, Richard;Parr, Michael;Tortella, Bartholemew;Champion, Howard R;Bernard, Gordon;Boffard, Kenneth;Bouillon, Bertil;Croce, Martin;Dimsits, Jeannett;Holcomb, John;Leppäniemi, Ari;Vincent, Jean Louis ;Hauser, Carl;CONTROL Study Group,
Référence The Journal of trauma, 71, 1, page (12-19)
Publication Publié, 2011-07

Article révisé par les pairs

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Résumé :

Safety data on recombinant activated factor VII (rFVIIa, NovoSeven; Novo Nordisk A/S, Bagsværd, Denmark) in actively hemorrhaging trauma patients are limited. We present detailed safety data from a large multicenter, randomized, placebo-controlled phase III study (the CONTROL trial).