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Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin.

par Delattre, Isabelle Karine;Musuamba, Flora T;Verbeeck, Roger K.;Dugernier, Thierry;Spapen, Herbert D. M.;Laterre, Pierre-Francois;Wittebole, Xavier;Cumps, Jean;Taccone, Fabio Silvio ;Vincent, Jean Louis ;Jacobs, Frédérique ;Wallemacq, Pierre
Référence Clinical biochemistry, 43, 6, page (589-598)
Publication Publié, 2010-04

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Titre:	Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin.
Auteur:	Delattre, Isabelle Karine; Musuamba, Flora T; Verbeeck, Roger K.; Dugernier, Thierry; Spapen, Herbert D. M.; Laterre, Pierre-Francois; Wittebole, Xavier; Cumps, Jean; Taccone, Fabio Silvio; Vincent, Jean Louis; Jacobs, Frédérique; Wallemacq, Pierre
Informations sur la publication:	Clinical biochemistry, 43, 6, page (589-598)
Statut de publication:	Publié, 2010-04
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	β-lactams
	Amikacin
	Multivariate analysis
	Pharmacokinetics
	Sepsis
	Therapeutic drug monitoring
MeSH keywords:	Adult
	Aged
	Aged, 80 and over
	Amikacin -- administration & dosage -- pharmacokinetics
	Anti-Bacterial Agents -- administration & dosage -- pharmacokinetics
	Calibration
	Critical Illness -- therapy
	Drug Dosage Calculations
	Drug Monitoring -- methods
	Drug Synergism
	Drug Therapy, Combination
	Empirical Research
	Female
	Humans
	Male
	Middle Aged
	Models, Theoretical
	Sepsis -- blood -- drug therapy
	Young Adult
	beta-Lactams -- administration & dosage
Note générale:	Evaluation Studies
	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0009-9120
	info:doi/10.1016/j.clinbiochem.2009.12.007
	info:pii/S0009-9120(09)00555-4
	info:scp/77950867085
	info:pmid/20036226