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T-cell large granular lymphocyte leukemia is characterized by massive TCRBV-restricted clonal CD8 expansion and a generalized overexpression of the effector cell marker CD57.

par Melenhorst, Jos;Eniafe, Rhoda;Follmann, Dean;Molldrem, Jeffrey;Kirby, Martha;El Ouriaghli, Frank ;Barrett, A John
Référence Hematology journal, 4, 1, page (18-25)
Publication Publié, 2003

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Titre:	T-cell large granular lymphocyte leukemia is characterized by massive TCRBV-restricted clonal CD8 expansion and a generalized overexpression of the effector cell marker CD57.
Auteur:	Melenhorst, Jos; Eniafe, Rhoda; Follmann, Dean; Molldrem, Jeffrey; Kirby, Martha; El Ouriaghli, Frank; Barrett, A John
Informations sur la publication:	Hematology journal, 4, 1, page (18-25)
Statut de publication:	Publié, 2003
Sujet CREF:	Cancérologie
MeSH keywords:	Adult
	Aged
	Antigens, CD57 -- analysis
	Autoimmune Diseases -- immunology -- pathology
	CD4-Positive T-Lymphocytes -- chemistry
	CD8-Positive T-Lymphocytes -- chemistry -- pathology
	Clone Cells -- pathology
	DNA, Neoplasm -- analysis
	Female
	Flow Cytometry
	Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
	Humans
	Leukemia, T-Cell -- immunology -- pathology
	Male
	Middle Aged
	Neoplastic Stem Cells -- chemistry -- pathology
	Receptors, Antigen, T-Cell, alpha-beta -- genetics
	T-Lymphocyte Subsets -- chemistry
Note générale:	Journal Article
Langue:	Anglais
Identificateurs:	urn:issn:1466-4860
	info:doi/10.1038/sj.thj.6200212
	info:pii/6200212
	info:pmid/12692516