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IL-23R and TCR signaling drives the generation of neonatal Vgamma9Vdelta2 T cells expressing high levels of cytotoxic mediators and producing IFN-gamma and IL-17.

par Moens, Emmanuelle ;Brouwer, Margreet ;Dimova, Tanya ;Goldman, Michel ;Willems, Fabienne ;Vermijlen, David
Référence Journal of leukocyte biology, 89, 5, page (743-752)
Publication Publié, 2011-05

Article révisé par les pairs

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Titre:	IL-23R and TCR signaling drives the generation of neonatal Vgamma9Vdelta2 T cells expressing high levels of cytotoxic mediators and producing IFN-gamma and IL-17.
Auteur:	Moens, Emmanuelle; Brouwer, Margreet; Dimova, Tanya; Goldman, Michel; Willems, Fabienne; Vermijlen, David
Informations sur la publication:	Journal of leukocyte biology, 89, 5, page (743-752)
Statut de publication:	Publié, 2011-05
Sujet CREF:	Immunologie
Mots-clés:	γδ
	Human
	Il-23
	Newborn
MeSH keywords:	Adult
	Antigens, Differentiation, T-Lymphocyte -- metabolism
	Cell Proliferation -- drug effects
	Cells, Cultured
	Dendritic Cells -- cytology -- drug effects -- metabolism
	Diphosphonates -- pharmacology
	Flow Cytometry
	Genes, T-Cell Receptor -- physiology
	Granzymes -- metabolism
	Humans
	Imidazoles -- pharmacology
	Infant, Newborn
	Interferon-gamma -- metabolism
	Interleukin-17 -- metabolism
	Perforin -- metabolism
	Receptors, Antigen, T-Cell, gamma-delta -- metabolism
	Receptors, Interleukin -- metabolism
	Signal Transduction
	T-Lymphocyte Subsets -- metabolism
Note générale:	Comparative Study
	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0741-5400
	info:doi/10.1189/jlb.0910501
	info:pii/jlb.0910501
	info:scp/79955794248
	info:pmid/21330350