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First epileptic seizure induced by occupational nickel poisoning.

par Denays, Roger ;Kumba, Claudine;Lison, Dominique;De Bels, David
Référence Epilepsia, 46, 6, page (961-962)
Publication Publié, 2005-06

Article révisé par les pairs

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Résumé :

Toxic causes of seizures are numerous: alcohol and other substances of abuse, drugs, and industrial and household products. However, in the absence of a clearly suggestive history and/or associated symptoms and signs, identification of the toxic origin of new-onset seizures may be extremely difficult. We report here the case of a patient admitted in our hospital after a single generalized tonic-clonic seizure. The remarkable coincidence that a colleague of his, with whom he was working to clean the same workshop, had been admitted 1 week earlier for respiratory distress, coma, and de novo nonconvulsive focal status epilepticus, led us to consider a possible toxicologic etiology. Urine analysis revealed a high nickel concentration, suggestive of acute nickel poisoning.